Alcohol implant (disulfiram) - Medically supervised treatment
Begin treatment in a safe, confidential setting.
What is a disulfiram implant?
Alcohol dependence is a complex condition that affects both mental and physical health. While medication alone is not a cure, selected pharmacological interventions can support abstinence as part of a broader treatment plan. One such option is disulfiram implantation, an aversive method that helps reduce the risk of relapse by discouraging alcohol use.
Disulfiram (commonly referred to as “Esperal” in parts of Europe) is a medication used in aversive therapy for alcohol dependence. A disulfiram implant involves the placement of disulfiram-containing tablets under the skin during a minor procedure performed under local anesthesia. The purpose of the implant is to support abstinence by triggering an unpleasant reaction if alcohol is consumed.
How does it work?
Disulfiram interferes with alcohol metabolism by inhibiting aldehyde dehydrogenase. If alcohol is consumed during therapy, acetaldehyde can accumulate and lead to a rapid onset of unpleasant symptoms (the disulfiram–alcohol reaction). The intensity depends on individual factors and the amount of alcohol consumed.
Possible symptoms may include:
- nausea and vomiting
- facial flushing
- headache
- palpitations
- shortness of breath
- dizziness and weakness
- anxiety or agitation
- sweating
- skin rash
In rare cases, severe reactions may occur, including serious cardiovascular or respiratory complications. For this reason, disulfiram therapy must be used only after medical qualification and with clear patient guidance.
- Respiratory depression
- Acute heart failure
- Loss of consciousness
- Arrhythmia
- Epilepsy
- Myocardial infarction
- Death
Implementation of an alcohol insert in Zeus Rehab
At Zeus Detox & Rehab, disulfiram implantation is performed in a sterile clinical setting by an experienced physician. We provide a discreet admission process, respect for patient dignity, and a confidential treatment model. Qualification includes medical history, assessment of contraindications, and verification of abstinence before the procedure.
Clinical Contact
Contact with the center is intended for providing information regarding inpatient treatment and coordinating next steps in a confidential and non-binding manner.
What does the disulfiram suture procedure look like at Zeus Rehab?
1. Medical qualification
We review your medical history, medications, and contraindications. We confirm abstinence prior to the procedure and explain expected effects, risks, and aftercare.
2. Implantation under local anesthesia
A minor procedure performed in a sterile setting. The duration is typically around 20–30 minutes.
3. Aftercare and clinical follow-up
You receive clear instructions on wound care and activity limits. If any adverse symptoms occur, you can contact our team immediately.
Important: Please maintain 24–72 hours of abstinence from alcohol prior to the procedure, as advised by the physician.
Disulfiram is not a standalone cure for alcohol dependence. For lasting recovery, it should be combined with therapeutic work on relapse prevention, lifestyle change, and psychological support. If you require inpatient treatment, we can coordinate next steps in a confidential, non-binding manner.
FAQ – DISULFIRAM / ESPERAL
Disulfiram is a medication used in aversive therapy for alcohol dependence. It works by interfering with alcohol metabolism and causing an unpleasant physical reaction if alcohol is consumed. The purpose of disulfiram therapy is to support abstinence, not to treat addiction on its own.
Disulfiram inhibits the enzyme aldehyde dehydrogenase. When alcohol is consumed during treatment, acetaldehyde accumulates in the body, leading to rapid onset of unpleasant symptoms. This reaction acts as a deterrent and helps reduce the risk of relapse.
A disulfiram implant is a form of long-acting therapy in which disulfiram-containing tablets are placed subcutaneously during a minor medical procedure. The implant releases the medication gradually over time and does not require daily dosing.
Disulfiram therapy is considered safe when used in appropriately selected patients and under medical supervision. Qualification includes a medical history review, assessment of contraindications, and confirmation of alcohol abstinence prior to treatment.
Consumption of alcohol during disulfiram therapy may cause a disulfiram–alcohol reaction. Symptoms can include nausea, vomiting, facial flushing, headache, palpitations, shortness of breath, dizziness, and anxiety. In rare cases, severe reactions may occur.
The duration of action depends on the formulation and individual factors, but disulfiram implants typically remain active for several months. The exact duration is determined by the physician during qualification.
No. Disulfiram is not suitable for all patients. It requires medical qualification and is contraindicated in certain medical conditions. It is most appropriate for patients who are motivated for abstinence and understand the risks of alcohol consumption during therapy.
No. Disulfiram does not cure alcohol dependence. It is a supportive pharmacological tool that may reduce relapse risk. Long-term recovery requires psychological therapy, behavioral change, and relapse prevention planning.
Yes. Disulfiram therapy is most effective when combined with psychological treatment, psychoeducation, and structured addiction therapy. Medication alone is not sufficient for sustained recovery.
Yes. Disulfiram implantation and related medical care are conducted in a confidential clinical setting, in accordance with medical privacy and confidentiality standards.
RELATED ALCOHOL TREATMENT OPTIONS
Empathy, Confidentiality, and Clinical Safety
The treatment process is conducted under conditions of full confidentiality, with respect for patient dignity and individual needs.
The discreet setting of the facility and the continuous presence of the medical team ensure a sense of safety, stabilization, and anonymity at every stage of treatment.