Naltrexone Implant

Confidential clinical contact. Medically supervised implantation as part of a comprehensive addiction treatment plan.

Naltrexone Implant

Overview

Alcohol and opioid dependence are complex conditions that affect both physical and mental health. In selected clinical cases, pharmacological interventions may be used to support abstinence and reduce the risk of relapse as part of a broader treatment strategy.

Naltrexone is an opioid receptor antagonist that has been used in addiction medicine for several decades. When clinically indicated, a naltrexone implant may help reduce cravings and block the reinforcing effects of alcohol and opioids, supporting patients during early recovery.

unhappy young woman

What Is Naltrexone?

Naltrexone is a medication classified as an opioid receptor antagonist. It works by blocking opioid receptors in the brain, thereby reducing or eliminating the euphoric effects associated with alcohol and opioid use. In addition, naltrexone may reduce cravings and compulsive substance-seeking behavior.
 
Naltrexone is available in several clinically approved forms:
•Oral tablets (e.g. Revia, Depade)
•Extended-release intramuscular injection (e.g. Vivitrol)
•Subcutaneous implant (naltrexone implant)

What Is a Naltrexone Implant?

A naltrexone implant is a sterile, slow-release formulation of naltrexone placed subcutaneously during a minor medical procedure performed under local anesthesia. The implant gradually releases the medication over a period of approximately 90–100 days.

The implant is fully biodegradable and does not require removal. Its purpose is to provide continuous opioid receptor blockade, reducing the likelihood of relapse caused by missed doses or intentional discontinuation of oral medication.

psychotherapy session indoors

When Is Naltrexone Used?

Naltrexone may be used as part of treatment for:
•Alcohol use disorder
•Opioid dependence (after complete detoxification)
 
In clinical practice, naltrexone is most extensively studied and commonly used in alcohol dependence. By blocking reinforcing effects, it may help reduce alcohol consumption and support abstinence.

In opioid dependence, naltrexone blocks the effects of opioids such as heroin, morphine, oxycodone, fentanyl, and tramadol. Because it can precipitate acute withdrawal, naltrexone may only be used after full opioid detoxification under medical supervision.

In selected cases, physicians may also consider naltrexone in the management of certain behavioral addictions, based on individual clinical assessment.

Effects of the Naltrexone Implant

Treatment with a naltrexone implant may be beneficial for patients who:
•Have difficulty adhering to daily oral medication
•Have experienced relapse due to discontinued treatment
•Require sustained receptor blockade during early recovery
 
Key clinical characteristics:
•Continuous medication release without daily dosing
•No development of pharmacological tolerance
•Reduction of alcohol intoxication and opioid effects
•Does not block natural reward pathways unrelated to opioids
 
Patients are still able to experience pleasure from everyday activities such as exercise, music, relationships, and social interaction.

Naltrexone Implant at Zeus Detox & Rehab

At Zeus Detox & Rehab, naltrexone implantation is performed in a sterile clinical environment by an experienced physician. The process is discreet, medically supervised, and preceded by careful qualification.

Clinical qualification includes:
•Medical history review
•Assessment of contraindications
•Verification of abstinence from opioids and alcohol
•Explanation of effects, risks, and aftercare

Clinical Contact

Contact with the center is intended for providing information regarding inpatient treatment and coordinating next steps in a confidential and non-binding manner.

Procedure Overview

1. Medical qualification
A detailed medical interview, review of medications, and diagnostic testing as indicated.

2. Implantation under local anesthesia
A minor procedure performed in sterile conditions, typically lasting 20–30 minutes.

3. Aftercare and follow-up
Clear post-procedure instructions, wound care guidance, and clinical follow-up.

Important:
Patients must maintain abstinence from alcohol and opioids for the period specified by the physician prior to implantation.

Role of Naltrexone in Comprehensive Treatment

Naltrexone is not a standalone cure for addiction. Long-term recovery requires addressing psychological, behavioral, and social factors contributing to substance use.
 
When indicated, naltrexone implantation may complement:
•Inpatient or outpatient addiction therapy
•Relapse prevention planning
•Psychological and psychiatric support
 
Our clinical team can coordinate further treatment steps in a confidential and non-binding manner.

FAQ - Naltrexone Implant

A naltrexone implant is a slow-release formulation placed under the skin to provide continuous opioid receptor blockade for approximately three months.

When performed after proper medical qualification and detoxification, naltrexone implantation is considered a clinically established procedure.

No. Naltrexone supports abstinence but does not treat the psychological aspects of addiction. Therapy and aftercare are essential.

Yes, but only after complete opioid detoxification, as naltrexone can precipitate withdrawal if opioids are present.

Yes. Admission, treatment, and communication are handled discreetly in accordance with medical confidentiality standards.

Empathy, Confidentiality, and Clinical Safety

The treatment process is conducted under conditions of full confidentiality, with respect for patient dignity and individual needs.
The discreet setting of the facility and the continuous presence of the medical team ensure a sense of safety, stabilization, and anonymity at every stage of treatment.