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Psilocybin – application of an organic chemical compound in medicine

Psilocybin – mushrooms are its main source – is one of the naturally occurring alkaloids with properties that influence human consciousness. It is an organic chemical compound that, when consumed, induces experiences described as mystical, spiritual, and often religious. Recent scientific studies reveal its therapeutic potential, opening new doors for modern medicine. Thanks to these studies, there is a chance to use this substance in treating disorders and addictions.

Psilocybin – key information

This compound belongs to the tryptamine group. Its sources are certain species of mushrooms, such as psilocybe mushrooms, notably Psilocybe cyanescens or Psilocybe semilanceata in Europe. These mushrooms are colloquially called magic mushrooms; there are over 200 species of them worldwide. It is one of the most commonly used substances that alter consciousness, known to science and undergoing research since 1960. How does psilocybin work?

Impact of psilocybin on the human body

After consumption, psilocybin alters the perception of reality and thinking, environmental perception, and affects emotions. The intensity of these changes depends on the dosage and individual characteristics of the person who took the substance. The first effects are felt as early as half an hour after ingestion, and its effects on the body can last up to 6 hours. During this time, various effects are observed:

  • perceptual changes, visual and auditory; individuals who have ingested this substance see geometric shapes, and colors change in saturation.
  • emotional changes, feelings of euphoria, calmness, increased empathy, and connection with the world emerge.
  • increased brain activity; studies have shown that psilocybin increases activity in various areas of the brain, which may lead to increased creativity and openness of thinking. Contrary to popular belief, it does not cause hallucinations but rather alters the perception of reality.

Application of the compound in medicine

The most promising studies on psilocybin focus on its potential use in treating various psychiatric disorders. Research conducted since the 1960s has shown that psilocybin can have significant effects in therapy for difficult-to-treat cases of depression. In 2017, experts from Imperial College London conducted studies with patients suffering from treatment-resistant depression and achieved initial successes using small doses of psilocybin. Patients reported mood improvement and reduction of depressive symptoms after just one session. In 2001, the FDA in the United States approved the use of this compound for treating obsessive-compulsive disorders. Psilocybin is also being studied as a supportive agent in treating alcohol addiction. Its ability to disrupt entrenched thought patterns can help patients break the cycle of addiction. In 2014, researchers from the University of Baltimore demonstrated the effectiveness of this compound in combating drug addiction.


The potential of psilocybin in medicine is immense. Research suggests it may be helpful in treating depression, anxiety, and certain substance addictions. Its application in treating psychiatric and emotional disorders opens new possibilities for patients, offering hope for a more effective and humane form of therapy. While most studies highlight the potential therapeutic benefits of this substance, it is important to administer it in a controlled environment under the supervision of specialists. Are you looking for a proven method to support addiction recovery? Do you need the help of an experienced doctor? Are you interested in modern therapy methods? Seek help from trusted places like Zeus Detox Rehab & SPA, a center for treating alcohol, drug, and medication addictions, where you’ll find essential support and assistance in a wonderful natural setting under the care of experienced medical professionals.

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